KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EOMES
All Species:
13.64
Human Site:
S474
Identified Species:
25
UniProt:
O95936
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95936
NP_005433.2
686
72732
S474
G
G
R
Y
G
V
Q
S
F
F
P
E
P
F
V
Chimpanzee
Pan troglodytes
XP_001165803
690
73333
S478
G
G
R
Y
G
V
Q
S
F
F
P
E
P
F
V
Rhesus Macaque
Macaca mulatta
XP_001093085
737
80029
S525
G
G
R
Y
G
V
Q
S
F
F
P
E
P
F
V
Dog
Lupus familis
XP_850738
688
72729
S476
G
G
R
Y
G
V
Q
S
F
F
P
E
P
F
V
Cat
Felis silvestris
Mouse
Mus musculus
O54839
707
74783
N495
G
G
R
Y
G
V
Q
N
F
F
P
E
P
F
V
Rat
Rattus norvegicus
XP_001061749
663
70857
N451
G
G
R
Y
G
V
Q
N
F
F
P
E
P
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514679
386
42515
D175
F
S
A
P
A
E
A
D
A
P
S
P
P
D
V
Chicken
Gallus gallus
XP_426003
399
44936
P188
G
A
R
Y
S
V
Q
P
F
F
Q
E
Q
F
V
Frog
Xenopus laevis
P79944
692
75925
F481
T
R
Y
S
V
Q
P
F
F
Q
D
Q
F
V
N
Zebra Danio
Brachydanio rerio
NP_571754
661
71990
H450
V
N
N
L
P
Q
N
H
R
F
Y
G
S
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
A618
N
H
L
A
G
A
G
A
G
A
S
E
H
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
V210
Y
S
T
F
R
T
F
V
F
R
E
T
E
F
I
Sea Urchin
Strong. purpuratus
XP_791266
946
105128
I585
P
V
V
N
A
A
N
I
A
M
G
Q
F
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80
96.5
N.A.
87.5
81.6
N.A.
25.6
52.4
62.1
57.5
N.A.
22.9
N.A.
24.7
23.6
Protein Similarity:
100
99.1
82.9
96.9
N.A.
89.3
83.9
N.A.
33.5
54.5
70.5
68.9
N.A.
35.2
N.A.
34.9
37.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
66.6
6.6
6.6
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
66.6
13.3
6.6
N.A.
20
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
16
16
8
8
16
8
0
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
8
62
8
8
0
% E
% Phe:
8
0
0
8
0
0
8
8
70
62
0
0
16
62
0
% F
% Gly:
54
47
0
0
54
0
8
0
8
0
8
8
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
8
8
8
0
0
16
16
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
8
8
0
8
8
0
8
47
8
54
8
0
% P
% Gln:
0
0
0
0
0
16
54
0
0
8
8
16
8
0
0
% Q
% Arg:
0
8
54
0
8
0
0
0
8
8
0
0
0
0
8
% R
% Ser:
0
16
0
8
8
0
0
31
0
0
16
0
8
0
0
% S
% Thr:
8
0
8
0
0
8
0
0
0
0
0
8
0
0
0
% T
% Val:
8
8
8
0
8
54
0
8
0
0
0
0
0
8
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
54
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _